ESPN 51th Annual Meeting

ESPN 2018


 
RESTLESS LEG SYNDROME IN CHILDREN WITH CHRONIC KIDNEY DISEASE
NURDAN YILDIZ 1 MEHTAP SAK 1 NESLIHAN CICEK 1 DILSAD TURKDOGAN 2 HARIKA ALPAY 1

1- MARMARA UNIVERSITY MEDICAL SCHOOL, DEPARTMENT OF PEDIATRIC NEPHROLOGY, ISTANBUL, TURKEY
2- MARMARA UNIVERSITY MEDICAL SCHOOL, DEPARTMENT OF PEDIATRIC NEUROLOGY, ISTANBUL, TURKEY
 
Introduction:

 

Restless leg syndrome (RLS), a sensory motor disorder, is common in patients with chronic kidney disease (CKD) and approximately one-quarter of adult patients with CKD suffer from RLS. Restless leg syndrome is thought to cause sleep disruption and reduce quality of life and school performance in children.There is limited information on RLS in children with CKD.

The aim of this study was to investigate the association between RLS and different stages of CKD in children.

Material and methods:

 

We conducted an observational cross-sectional study on 44children aged 5–18 years in all stages of CKD at ouroutpatient clinic. After a full explanation of the study, informed consent was obtained and the International Restless Leg Syndrome Study Group questionnaire (IRLSSG) was performed by personal interview to evaluate RLS during the periodic outpatient visits. Demographic, clinical and laboratory data were recorded from the medical files of the patients.

Results:

 

Seventeen males(60.4%) and 27 females(39.6%) children with CKD were included in the study. The mean age and the follow-up of the patients were 13.2±5.2 (5-23) and 5.3±4.3 years, respectvely. Glomerular filtration rate of the patients was 32.7±0.97 and nine patients were on dialysis therapy (six peritoneal dialysis and three hemodialysis). Thirty-two patients were on stage three or four CKD. The underlying etiologies of CKD were CAKUT (congenital abnormalities of the kidney and urinary tract) in 22(50%) patients, hereditary diseases in five(11.3%), neurogenic bladder in six(13.6%) and autosomal recessive polycystic kidney disease in three(6.8%) patients.

None of the children met the RLS criteria in our study but we identified twoparents having RLS.

Conclusions:

 

Our results revealed that RLS is rare in children with any stage of the CKD. However, our study was limited due to small sample size. Further studies with large series are required to investigate the RLS in children with CKD.