ESPN 51th Annual Meeting

ESPN 2018


 
Retrospective Evaluation Of Children Diagnosed With Henoch- Schönlein Purpura
MEHTAP AKBALIK KARA 1 BELTINGE DEMIRCIOĞLU KILIÇ 2 MITHAT BÜYÜKÇELIK 2 AYŞE BALAT 3

1- DIYARBAKIR CHILDRENS HOSPITAL DEPARTMENT OF PEDIATRIC NEPHROLOGY
2- GAZIANTEP UNIVERSITY FACULTY OF MEDICINE, DEPARTMENT OF PEDIATRIC NEPHROLOGY
3- İSTANBUL AYDIN UNIVERSITY FACULTY OF MEDICINE, DEPARTMENT OF PEDIATRIC NEPHROLOGY AND RHEUMATOLOGY
 
Introduction:

 Henoch-Schöenlein purpura (HSP) is the most common vasculitis in children characterized by non-thrombocytopenic purpura, arthritis or arthralgia, gastrointestinal system (GIS) and renal involvement. Long-term prognosis is associated with renal involvement.

Material and methods:

 We retrospectively rewieved HSP patients whom attended to pediatric nephrology clinic of Gaziantep University Hospital between January 2015 and January 2017. We analyzed their epidemiological profile, clinical and laboratory features, follow-up findings and prognosis. Logistic regression analysis performed to identify risk factors associated with renal involvement in HSP patients.

Results:

 Average age of patients was 7.90±2.81 years, and  male to female ratio at 0.93:1. The most common triggers were upper respiratory tract infections, especially in autumn and winter seasons. Of the 118 patients 104 had arthritis,  most commonly in lower extremities. A hundred and three patients (87.3 %) had gastrointestinal involvement and 31 (26,3%) had kidney damage. Twenty three patients were underwent to renal biopsy

Conclusions:

 Scrotal involvement,C-reactive protein(CRP) increased  levels, the duration and severity of skin involvement, gender, age and mean platelet volume are not found to have potential risk factors for renal involvement.  However, all HSP patients should be followed closely for renal involvement.

Key words: Henoch-Schönlein purpura, nephritis, risk factors