ESPN 51th Annual Meeting

ESPN 2018


 
Peritoneal dialysis (PD) in infants below 6 months of age
ANGELIQUE DACHY 1 JUSTINE BACCHETTA 1 ANNE-LAURE SELLIER-LECLERC 1 AURELIA BERTHOLET-THOMAS 1 DELPHONE DEMEDE 1 PIERRE COCHAT 1 BRUNO RANCHIN 1

1- HOSPICES CIVILS DE LYON ET UNIVERSITé LYON1, BRON, FRANCE
 
Introduction:

Little information is available for infants who started RRT before 6 months of age. Uncertain outcomes raise the question whether PD in neonates and infants is justified. 

Material and methods:

We performed a retrospective analysis of the data of all patients below 6 months of age who began chronic PD in our unit between January 2007 and January 2017. Results are presented as median(min;max).

Results:

5 girls and 8 boys were included(6 prenatal diagnoses,2 premies) with the following diagnoses: CAKUT(N=7),oxalosis(N=4) and congenital nephrotic syndrome(N=2).7 patients presented associated co-morbidities. At PD initiation, age was 2.7(0.2;5.9) months, height-SDS-1.05(-5.73;0.61) and weight-SDS-1.28(-2.77;0.66). PD duration was 11.9(2.2; 32.0) months, and at PD discontinuation height-SDS was-0.94(-4.34;0.73),weight-SDS-0.72(-2.25;0.20),PTH levels 109(44;1540)ng/L, and hemoglobin levels 110(73;136)g/L.10 patients presented a total of 19 peritonitis. Causes of PD discontinuation were: switch to hemodialysis(N=4),transplantation(N=5)and recovery of renal function(N=3).With a follow-up of 4.7(2.8;10.7)years, 9 patients are transplanted (2graft losses because of thrombosis), 1 patient is still on PD, 1 patient is on hemodialysis and 2 patients had spontaneous recovery of renal function. Four patients displayed neurodevelopmental delay with 2 patients currently needing special schooling. 

Conclusions:

Our data confirm that most of those infants will have a favorable outcome.