ESPN 51th Annual Meeting

ESPN 2018


 
ACUTE KIDNEY INJURY IN TERM INFANTS: A SINGLE-CENTER REPORT
EMEL OKULU 1 AYBIKE YILMAZ 2 EDA SUZEN 2 DIDEM EDA SUKUR KURT 3 ECE MEKIK 3 SAADET ARSAN 1 MESIHA EKIM 3

1- ANKARA UNIVERSITY FACULTY OF MEDICINE, DEPARTMENT OF PEDIATRICS, DIVISION OF NEONATOLOGY
2- ANKARA UNIVERSITY FACULTY OF MEDICINE, DEPARTMENT OF PEDIATRICS
3- ANKARA UNIVERSITY FACULTY OF MEDICINE, DEPARTMENT OF PEDIATRICS, DIVISION OF PEDIATRIC NEPHROLOGY
 
Introduction:

Acute kidney injury (AKI) is a common event in neonatal intensive care units (NICUs). The aim of this study is to investigate the incidence of and risk factors for AKI in term infants who were admitted to NICU.  

Material and methods:

This is a retrospective cohort study of term infants admitted to our NICU between January 1,2017 and December 31,2017. Infants who had congenital renal anomalies, died within the first 3-days, had only one datum of serum creatinine level during admission, transfered from another center after 3 day postnatally were excluded. Demographic, clinical and laboratory data of the included infants were analyzed. Diagnosis of AKI was based on the neonatal AKI KDIGO classification criteria.

Results:

During the study period 398 term infants were admitted to NICU. Two-hundred-fourty-nine(62.5%) infants were excluded due to one creatinine level in 202, transfered from other center in 30, congenital renal anomaly in 14, death in first 3-days in 3 infants. Total of 149 term infants were evaluated. AKI occured in 6%(n=9) of 149 infants. Stage-1, stage-2, and stage-3 AKI occured in 3.3%, 2%, and 0.7% of infants, respectively.  All these infants were born from an uneventful pregnancy. The diagnosis in 3 (33%) of 9 infants was hypoxic ischemic encephalopaty. Six(67%) infants had umbilical artery catheter, 4(44%) infants received respiratory support, 1(11%) infant received ECMO support, aminoglycoside was used in 3 (33%) infants, 5(55%) infants received inotrops, and renal replacement therapy initiated in 3(33%) infants. Two(22%) infants died.

Conclusions:

Identification of AKI is important in this population. It is often multifactorial, and close follow-up of all neonates with a history of AKI is crucial for early detection of long term complications.