ESPN 51th Annual Meeting

ESPN 2018


 
INFLUENCE OF PERITONEAL TRANSPORT CHARACTERISTICS ON CLINICAL OUTCOME IN CHILDREN WITH PERITONEAL DIALYSIS
NESLIHAN GUNAY 1 AYSE SEDA PINARBASI 1 SIBEL YEL 1 JALE DURSUN 2 SIBEL BOLAT 2 ISMAIL DURSUN 1 DEMET GUNAY 2 MUAMMER HAKAN POYRAZOGLU 1 RUHAN DUSUNSEL 1

1- ERCIYES UNIVERSITY, PEDIARTRIC NEPHROLOGY, KAYSERI
2- ERCIYES UNIVERSITY, PEDIARTRIC NEPHROLOGY, PERITONEAL DIALYSIS UNIT, KAYSERI
 
Introduction:

The peritoneal equilibration test (PET) is a semiquantitative test used to evaluate the permeability of the peritoneal membrane. Peritoneal transport status is an important prognostic factor for patients undergoing peritoneal dialysis (PD). The aim of this study was to evaluate the relationship between peritoneal transport status and some clinical-biochemical parameters of children with PD treatment.

 

Material and methods:

 Fifty-five patients treated with PD were included in to study. Mean age was 9.8 ± 4.7 years. Patients were classified as high and low peritoneal permeability groups according to creatinin, urea and glucose transport status. Age, sex, body mass index, comorbidities, residual renal clearance of creatinine, total weekly clearance of urea (KprTw/V), number of PD-related peritonitis and hospitalization per patient-year, mortality rate, median weekly erythropoietin dose and biochemical parameters of patients were evaluated between these groups.

Results:

 Patients with high permeability for creatinine had significantly low values of residual renal clearance of creatinine, lower HCO3 levels and higher rates of mortality and hospitalization compared to low creatinine permeability group. Patients with high permeability for glucose had significantly low values of residual renal clearance of creatinine, and KprTw/V, higher rates of hospitalization compared to low glucose permeability group. Higher peritonitis rates were found in the group with high urea permeability.

Conclusions:

 High peritoneal permeability for creatinine and glucose are poor prognostic factors that affect hospitalization rates in patients with PD. Patients with higher permeability for creatinine and glucose have lower residual renal creatinine clearance.