ESPN 51th Annual Meeting

ESPN 2018


 
ETIOLOGICAL STRUCTURE OF URINARY TRACT INFECTIONS IN NEWBORNS
ALEXANDRA KRUTOVA 1 ELENA MELNIKOVA 1 VALENTINA LUCHANINOVA 2 ELENA ZAITSEVA 3 OLGA SEMESHINA 1

1- REGIONAL CHILDREN’S CLINICAL HOSPITAL № 1, VLADIVOSTOK, RUSSIAN FEDERATION
2- NORTH-WESTERN STATE MEDICAL UNIVERSITY NAMED AFTER I.I. MECHNIKOV, SAINT PETERSBURG, RUSSIAN FEDERATION
3- PACIFIC STATE MEDICAL UNIVERSITY, VLADIVOSTOK, RUSSIAN FEDERATION
 
Introduction:

Number of urinary tract infections (UTI) in the neonatal period has increased in recent years. Verification of the diagnosis of UTI in newborns is difficult even in the presence of clinical manifestations. The main diagnostic method is a bacteriological urine culture. Modern knowledge of the prevailing bacterial uropathogens and susceptibility to antibiotics promote adequate initial antibiotic therapy. The aim of this study was to estimate the microbial spectrum of urine in newborns with UTI.

Material and methods:

The analysis of 816 results of bacteriological urine cultures samples of newborns with UTI was carried out with the calculation of the average specific gravity of the allocated uropathogens for 10 years.

Results:

Etiologically significant for many of urinary tract infections in the neonatal period has been E. faecalis with a specific gravity of 52 % to 75% in different years, an average of 53.38% . E. coli allocated less (an average of 33,18%). The third frequency was determined by Enterobacter spp. (more often E. coseri), the specific gravity of it ranged from 4.3% to 14.7% and was higher than in patients with UTI of another age, in which the third most significant was P. mirabilis. Such microorganisms as Citrobacter spp., Ps. aeruginosa, P. mirabilis, C. albicans, were allocated in isolated cases. For ten years at newborns the highest antibiotic resistance of the allocated uropatogen is noted.

Conclusions:

The microbial spectrum of urine in newborns with UTI is more scarce and differs from the etiological structure of UTI in children of other ages. The reasons for the predominance of the etiological significance of E. faecalis in the development of UTI in the neonatal period can be considered functional immunodeficiency in this category of patients and the participation of this uropathogen in the development of Healthcare-associated infections.