ESPN 51th Annual Meeting

ESPN 2018


 
ANEMIA IN PEDIATRIC RENAL TRANSPLANT RECIPIENTS
AHMET KAHVECI 1 Z BIRSIN ÖZÇAKAR 1 NILGÜN ÇAKAR 2 BEYZA DOĞANAY ERDOĞAN 3 FATOŞ YALÇINKAYA 2

1- ANKARA UNIVERSITY FACULTY OF MEDICINE, PEDIATRICS, ANKARA TURKEY
2- ANKARA UNIVERSITY FACULTY OF MEDICINE, PEDIATRIC NEPHROLOGY, ANKARA TURKEY
3- ANKARA UNIVERSITY FACULTY OF MEDICINE, BIOISTATISTICS, ANKARA TURKEY
 
Introduction:

 Anemia is a common complication in pediatric renal transplant recipients associated with several risk factors. The aim of the study was to determine the frequency and risk factors of anemia in children with a renal allograft and the association of post-transplant anemia (PTA) with graft function.

Material and methods:

 A single center retrospective study was performed. Patients who have had kidney transplantation between March 2008-March 2017were included to the study. Anemia was defined according to age and gender-adjusted reference values of hemoglobin (Hb) for children.

Results:

 A total of 62 patients (34 male; medianage of 217 (80-284) months;8 received a preemptive transplant with 29% of organs coming from deceased donors) were enrolled in the study. The patients underwent renal transplantation at a median age of 153.5 (26-234) months. Anemia developed in 39(63%) patients with a median follow up of 50 (3-156) months. Mean Hb level of anemic patients was 9.6±2g/dl. The most prevalent cause of PTA was iron deficiency, seen in 27 (44%) patients, followed by anemia of chronic kidney disease, bone marrow suppression, deficiency of folic acid and B12 in 34%, 11%, 11% and 7%, respectively. Ninety percent of the patients with anemia improved with treatment. During follow up period growth parameters of the patients with anemia did not differ from the patients without. Hemoglobin levels were found to be significantly lower in the patients with eGFR less than 60ml/min/1.73m2 as compared with the ones higher.

Conclusions:

 Although anemia is highly prevalent in pediatric kidney graft recipients recovery is high with early diagnosis and appropriate treatment. Anemia seems not to effect growth in post-transplant period. However, decrease in GFR is one of the most important risk factors for PTA.