ESPN 51th Annual Meeting

ESPN 2018


 
Progression of left ventricular hypertrophy after renal transplantation in children
HANAN ABDELAZIZ HAFEZ BAZARAA 1

1- CAIRO UNIVERISTY CHILDREN HOSPITAL
 
Introduction:

 There is accumulating evidence that those with childhood-onset end-stage renal disease (ESRD) are at increased cardiovascular risk. Left ventricular hypertrophy (LVH)  is predictors of cardiovascular morbidity and mortality in  those patientspatients .

Aim: of the study: to determine the occurrence and progression of LVH in Pediatric renal transplant recipients and to identify the associated risk factors.

Material and methods:

 The study included 21 patients transplanted at Cairo University Children hospital   . They were subjected to clinical and routine laboratory assessment, as well as echocardiographic assessment of LV mass, geometry and function, just before transplantation and at the end of the first post-transplant year.

Results:

 Before transplantation, the mean LVM was 72.1±26.9 g and LVMI was 74.7±31.7 g/m². one year after transplantation (more than 90 % had above 80ml/min GFR LVM:103.4±39g,LVMI:100.5±28.3g/m2 . Left ventricular hypertrophy was present in 43% of cases before transplantation (eccentric in 14%, concentric in 10%),  additional 19% having concentric remodeling. One year after transplantation, this percentage was increased totally to 76%(new ,worsening cases are: 47.6%) ,concentric hypertrophy in  more than 30%
Risk factors for LV worsening after transplantation :dyslipidemia and rejection episodes , diastolic blood pressure index 

Conclusions:

 left ventricular hypertrophy, occur in renal transplant children before and after transplantation  , related risk factors(hypertension, obesity, hyperlipidemia, rejection episodes) is still present after successful renal transplantation.