ESPN 51th Annual Meeting

ESPN 2018


 
Congenital anomalies of kidney and urinary tract are associated with higher mortality in Neonatal Unit Care
LAIS FAGUNDES PASINI 2 BRENO FAUTH DE ARAúJO 1 LUCIANO DA SILVA SELISTRE 2 VANDREA DE SOUZA 2

1- UNIVERSIDADE DE CAXIAS DO SUL
2- PROGRAMA DE PóS GRADUAÇãO EM CIêNCIAS DA SAúDE, UNIVERSIDADE DE CAXIAS DO SUL
 
Introduction:

  We aimed to evaluate the prevalence of CAKUT in the last 18 years of a neonatal intensive care unit (NICU) and compare the perinatal mortality rate among fetuses with CAKUT and the others.

Material and methods:

  Cross-sectional study including all newborns admitted to the NICU between March 1998 and December 2016. A Cox proportional hazards model was applied to evaluate the relative hazard of death in the two groups, adjusted for maternal diabetes, complex malformations and very low birth weight.

 

 

Results:

  From 7,984 newborns admitted in the NICU during the study period, CAKUT were diagnosed in 127 (1.5%). Eleven percent of mothers in the CAKUT group and 5.0% in the non-CAKUT group had gestational diabetes (P<0.01). The mortality rate was 32.2% in the CAKUT group and 9.5% in the non-CAKUT group. The odds of mortality was 8.9 times (95% CI: 5.8 – 13.4) in the CAKUT group than in the control group.

Conclusions:

  The prevalence of CAKUT was similar to other studies looking to tertiary hospitals. The presence of CAKUT has implications for mortality and early detection and treatment of this pathology allows preserving renal function and instituting necessary intervention measures.