ESPN 51th Annual Meeting

ESPN 2018


 
Nosocomial Urinary Tract Infection in Pediatrics; Etiology and Antibiotic Susceptibility Results
FATMA DEVRIM 1 ERKIN SERDAROGLU 1 İLKNUR ÇAĞLAR 2 NEVBAHAR DEMIRAY 2 YELIZ YAMAN ORUC 2 YELDA SORGUC 3 NURI BAYRAM 2 YÜCE AYHAN 3 HASAN AGIN 4 ŞEBNEM ÇALKAVUR 5 EBRU YILMAZ 1 NIDA DINÇEL 1 ORHAN DENIZ KARA 1 ILKER DEVRIM 2

1- DEPARTMENT OF PEDIATRIC NEPHROLOGY, DR.BEHCET UZ CHILDRENS HOSPITAL, İZMIR/TURKEY
2- DEPARTMENT OF PEDIATRIC INFECTIOUS DISEASE, DR.BEHCET UZ CHILDRENS HOSPITAL, İZMIR/TURKEY
3- DEPARTMENT OF MICROBIOLOGY AND CLINICAL MICROBIOLOGY ,DR.BEHCET UZ CHILDRENS HOSPITAL IZMIR/TURKEY
4- PEDIATRIC INTENSIVE CARE UNIT ,DR.BEHCET UZ CHILDRENS HOSPITAL IZMIR/TURKEY
5- NEONATAL INTENSIVE CARE UNIT ,DR.BEHCET UZ CHILDRENS HOSPITAL IZMIR/TURKEY
 
Introduction:

Nosocomial urinary tract infections (nUTIs) common problem especially intensive care units (ICU) and can cause with prolongation of hospitalization, morbidity and mortality. Symptomatic nUTIs is the second common cause of nosocomial infection in pediatric intensive care units. The aim of the study was to evaluate pathogenic causes and antimicrobial susceptibility rates in catheter related or unrelated symptomatic nUTIs.

Material and methods:

All symptomatic nUTIs in pediatric, neonatal and surgery ICUs between January 2014 and December 2017 was recorded. Positive urine culture with any related symptoms and acute-phase reactant elevations was accepted as nUTIs.

Results:

A total 138 nUTIs episode was found. There was 26 (18.8%) episode with related urinary catheters and 112(81.2%) with non-catheter related. Klebsiella spp, E.coli and P.aeroginosa was isolated 34.8%, 19.6% and 9.4% in urine cultures respectively. Extended spectrum beta lactamase (ESBL) positivity was 82.7% in Klebsiella spp and 72.9% in E.coli. Resistance to meropenem and quinolones were found 38.5% and 46.2% in P.aeroginosa. Eighteen percent of Klebsiella spp and 7.4% of E.coli were resistant to meropenem. Also 45.9% of Klebsiella spp and 14.8% of E.coli were resistant to ertapenem.

Conclusions:

Most data on resistance patterns of nUTIs are limited to adults. In our study we found high rate of meropenem resistance in P.aeroginosa, and ESBL production in E.coli and Klebsiella spp. The higher rates of ertapenem resistance and ESBL positivity in nUTIs are worrying about the development of multi-drug resistant infections in the future.