ESPN 51th Annual Meeting

ESPN 2018


 
Is urinary screening useful for the prevention of renal and cardiovascular diseases?
TERESA PAPALIA 1 ROSITA GRECO 1 DANILO LOFARO 2 AGATA MOLLICA 1 FRANCESCO MOLLICA 1 RENZO BONOFIGLIO 1

1- NEPHROLOGY DIALYSIS AND TRANSPLANTANTION DEPARTMENT. ANNUNZIATA HOSPITAL. COSENZA-ITALY
2- **KIDNEY AND TRANSPLANTATION RESEARCH CENTER. ANNUNZIATA HOSPITAL . COSENZA- ITALY.
 
Introduction:

Urinary abnormalities in pediatric age may be the indicator of the onset of certain kidney diseases in adulthood. Given the high social impact of chronic kidney disease it is necessary to study preventive strategies to block the progression of kidney damage already in pediatric age. The aim of this work is to analyze the usefulness of a urinary screening in a student population. 

Material and methods:

In 1024 students of mean age of 15.01 ± 1.21 BC (600M, 524 F) urine dipstick were performed and detected blood pressure and medical history. The students with urinary abnormalities were subsequently re-evaluated on an outpatient basis.

Results:

14.7% of the sample examined showed isolated microhematuria. At subsequent evaluations, microhematuria was transitory in 9% of cases, secondary to kidney stones in 4% and urinary tract infections in 1.7%. An isolated proteinuria was present in 12.4%. Proteinuria was functional and / or secondary to urinary tract infections in 60% and 38% of cases, while in 2 patients it was associated with microhematuria. Both patients underwent renal biopsy that showed a glomerulonephritis with mesangial IgA deposits. Leukocyturia was present in 7.2% of cases, especially in girls. 12.5% of the students were hypertensive (PAS AND / OR PAD ≥ 95th) and among these, 7% of them had a positive family history for hypertension and cardiovascular disease.

Conclusions:

Our study raises the question of whether or not screening in unselected populations is useful, given the low number of glomerular diseases that have been detected. This doubt, the subject of international debate, however, can not make us forget that preventing and treating kidney disease as soon as possible also means preventing cardiovascular diseases.