ESPN 51th Annual Meeting

ESPN 2018


 
FEATURES OF THE CONGENITAL ANOMALIES OF THE KIDNEY AND URINARY TRACT IN 100 CHILDREN WITH CAKUT
IRINA KUTYRLO 1 NADEZHDA SAVENKOVA 1

1- SAINT-PETERSBURG STATE PEDIATRIC MEDICAL UNIVERSITY
 
Introduction:

Identification the features of the congenital anomalies of the kidney and urinary tract in 100 children with  CAKUT.

Material and methods:

100 children (57 boys and 43 girls) with CAKUT, aged 2 months to 17 years, were examined. Stage C1-C5 of chronic kidney disease (CKD) classified by glomerular filtration rate (GFR) in Schwartz formula.

Results:

From 100 patients 94 (94%) were isolated and 6 (6%) were CAKUT syndromatic  (VCTERL-Association, syndromes Laurence – Moon – Bardet – Biedls,  Rubinstein– Taybi , Lowe, Renal-Coloboma). In 100 children with CAKUT diagnostic combination congenital  anomalies kidneys: unilateral or bilateral hypoplasia (39%), duplex  (17%), dystopia (9%), agenesis (5%), horseshoe (17%), ectopic (11%), multicycstic dysplastic and  polycystic kidneys (2%); urinary tract: vesicoureteral reflux (VUR) (51%),  hydronephrosis and hydroureter (33%), diverticulae bladder (1%), posterior urethral valves (3%), double ureters (2%), hydronephrosis/ hydroureter and  VUR (10%). In 6 children with syndromatic CAKUT diagnosed kidneys hypoplasia (2), multicycstic dysplastic (1), duplex (1), ectopic (1) and ureterohydronephrosis (3), VUR (3), rudimental ureter unilateral (1). Stratification of stage  CKD C1-5 was performed taking into account the GFR in 85 children (aged 2 - 17 years) with CAKUT: C1 in 63 (74%), C2 in 4 (4.7%), C3 in 5 (6%), C4 in 8 (9.3%), C5 in 5 (6%).

Conclusions:

In structure CAKUT in 100 children dominated anomalies of the kidneys (hypoplasia), anomalies of the urinary tract (VUR, hydronephrosis / hydroureter).