ESPN 51th Annual Meeting

ESPN 2018


 
CLINICAL SPECTRUM OF CONGENITAL ANOMALIES OF KIDNEY AND URINARY TRACT: 14 YEARS EXPERİENCE IN SINGLE CENTER
HÜSEYIN SALIH GÜNGÖR 1 KENAN BEK 1 MEHTAP EZEL ÇELAKIL 1 BURCU BOZKAYA YÜCEL 1 ZELAL EKINCI 1

1- KOCAELI UNIVERSITY FACULTY OF MEDICINE DEPARTMENT OF PEDIATRIC NEPHROLOGY
 
Introduction:

 Congenital anomalies of kidney and urinary tract (CAKUT) are among the most common pediatric congenital anomalies and constitute 30-60 % of end stage renal disease population in various societies. 

Material and methods:

 Charts of 11725 pediatric nephrology outpatients followed within 14 years (2002-16) in our center were reviewed. A total of 461(3.9%) children with CAKUT were included after excluding 4164 patients with transient hydronephrosis.  Along with diagnostic categorization; clinical, demographic and epidemiological characteristics of patients were retrospectively analyzed. 

Results:

      Overall CAKUT frequency was 3.9% of all outpatient population almost equally effecting boys and girls (48.8% boys). VUR was detected in 31.5% of the patients, more frequent in girls (71.7%). Hydronephrosis was present in 16.2% of the patients and their antenatal detection rate was only 30.7%. Ureteropelvic obstruction (70.2%) and VUR (14.4%) were the most common anomalies accompanying hydronephrosis. Urinary tract infection was frequent (50.5%) and it was significantly higher (90.3%) in patients with VUR. Eight patients progressed to ESRD and underlying cause was VUR in four of them.

Conclusions:

 CAKUT in children is a relatively common condition. The risk of chronic kidney disease and progression to ESRD is considerably high. Therefore these children, excluding transient hydronephrosis cases, should be managed in tertiary care reference centers by  a multidisciplinary approach.